4 years ago
I would like to preserve leukocytes for future epigenetic analysis. How can I preserve them effectively in order to perform DNA methylation profiling at a later time?
For DNA methylation profiling you only need the DNA, so a good way is to isolate the DNA first and then store the DNA at -20°C. You can also snap-freeze the cells using liquid nitrogen and then store the cells at -20°C and isolate the DNA later. For single cell DNA methylation profiling, probably fresh cells are the best,