DNA isolation / purification Tissue

Get tips on using Quick-Load® Purple Low Molecular Weight DNA Ladder to perform DNA Ladder Low Range

Get tips on using BH100bp ladder :: GD 100bp DNA Ladder H3 RTU Ladder to perform DNA Ladder 100 bp

Get tips on using Quick-Load® Purple 1 kb Plus DNA Ladder to perform DNA Ladder 1 kb

Get tips on using E-Gel™ 1 Kb Plus Express DNA Ladder to perform DNA Ladder 1 kb

Get tips on using ApoAlert™ DNA Fragmentation Assay Kit to perform TUNEL assay cell type - A549, NCI-H460, H1299 human alveolar carcinoma

Get tips on using TRIzol Reagent to perform RNA isolation / purification Cells - immortalized Daudi

Get tips on using TRIzol Reagent to perform RNA isolation / purification Cells - immortalized Daoy

Get tips on using ISOGEN to perform RNA isolation / purification Cells - immortalized CHO

I would like to excise a large strand of DNA and insert a new one using CRISPR. My problem is that my strand will be a little over 1kb and I am not sure if this is going to be a limiting factor. Also, how long should the homology arms be for a region of this size?