shRNA gene silencing Human Islets of langerhans ZEB1

DNA microarrays enable researchers to monitor the expression of thousands of genes simultaneously. However, the sensitivity, accuracy, specificity, and reproducibility are major challenges for this technology. Cross-hybridization, combination with splice variants, is a prime source for the discrepancies in differential gene expression calls among various microarray platforms. Removing (either from production or downstream bioinformatic analysis) and/or redesigning the microarray probes prone to cross-hybridization is a reasonable strategy to increase the hybridization specificity and hence, the accuracy of the microarray measurements.

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Get tips on using ON-TARGETplus Mouse Hspa5 (14828) siRNA - SMARTpool to perform siRNA / miRNA gene silencing Mouse - MC3T3-E1 Grp78/Hspa5

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Get tips on using ON-TARGETplus Mouse Mapk14 (26416) siRNA - SMARTpool to perform siRNA / miRNA gene silencing Mouse - MC3T3-E1 p38/Mapk14